Collagens-structure, function, and biosynthesis
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than 20 different collagen types
Demineralization–remineralization dynamics in teeth and bone
Biomineralization is a dynamic, complex, lifelong process by which living organisms control precipitations of inorganic nanocrystals within organic matrices to form unique hybrid biological tissues, for example, enamel, dentin, cementum, and bone.
Dental Enamel Development: Proteinases and Their Enamel Matrix Substrates
This review focuses on recent discoveries and delves in detail about what is known about each of the proteins (amelogenin, ameloblastin, and enamelin) and proteinases (matrix metalloproteinase-20 and kallikrein-related peptidase-4) that are secreted in
DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE
Dental enamel is the hardest substance in the human body and serves as the wear-resistant outer layer of the dental crown. It forms an insulating barrier that protects the tooth from physical, thermal, and chemical forces that would otherwise be injuri
Dental erosion in children and adolescents – a cross-sectional and longitudinal investigation using study models
To investigate the prevalence and incidence of dental erosion in children and adolescents.
Dentin: Structure, Composition and Mineralization: The role of dentin ECM in dentin formation and mineralization
A thick dentin layer forms the bulk of dental mineralized dental tissues. Dentin is capped by
a crown made of highly mineralized and protective enamel, and in the root, it is covered by
cementum, a structure implicated in the attachment o
Development of the Human Temporomandibular Joint
A great deal of research has been published on the development of the human temporomandibular joint (TMJ). However, there is some discordance about its morphological timing.
Glycan Recognition at the Saliva – Oral Microbiome Interface
The mouth is a first critical interface where most potentially harmful substances or pathogens contact the host environment. Adaptive and innate immune defense mechanisms are established there to inactivate or eliminate pathogenic microbes that travers
Histological Changes of the Mandibular Condyle in the Human Fetus at Early Stages of Gestation
During development of the human fetus, the secondary cartilage appears later in the mandibular condyle in the embryonic stage, and this cartilage is independent of primary skeletal cartilage.
Host response mechanisms in periodontal diseases
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans
Oral Cavity-Associated Immune System: What is New?
Although several excellent articles have reviewed different aspects of mucosal associated lymphoid tissues (MALT), there is not enough information about the oral cavity immune response.
Salivary Defense Proteins: Their Network and Role in Innate and Acquired Oral Immunity
There are numerous defence proteins present in the saliva. Although some of these molecules are present in rather low concentrations, their effects are additive and/or synergistic, resulting in an efficient molecular defence network of the oral cavity.
SALIVARY GLANDS AND SALIVA Number 2 Saliva - the defender of the oral cavity
is generally accepted that saliva is of paramount importance for the maintenance of oral health. This is based on the numerous studies reporting subjective and objective functional losses that occur in persons who lack the ability to produce adequate v
The mucosal immune system in the oral cavity—an orchestra of T cell diversity
The mucosal immune system defends against a vast array of pathogens, yet it exhibits limited responses to commensal microorganisms under healthy conditions.